Molecular Formula | C16H14N2O2S2 |
Molar Mass | 330.42 |
Solubility | DMSO: ≥ 51 mg/mL |
Storage Condition | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
In vitro study | TTP 22 is a potent CK2 inhibitor, with an IC 50 of 100 nM and a K i of 40 nM. TTP 22 shows no effect on other kianses such as Jnk3, Rock1, Tie2, Ask1, Met and FGFR1 at 10 μM. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.026 ml | 15.132 ml | 30.264 ml |
5 mM | 0.605 ml | 3.026 ml | 6.053 ml |
10 mM | 0.303 ml | 1.513 ml | 3.026 ml |
5 mM | 0.061 ml | 0.303 ml | 0.605 ml |
biological activity | TTP22 is a casein kinase 2 (CK2) inhibitor with an IC50 value of 100 nM. It is selective for CK2 and has no inhibitory activity for JNK3, ROCK1 and MET at a concentration of 10 μM. |
target | TargetValue CK2 () 100 nM |
Target | Value |
CK2 () | 100 nM |
in vitro study | TTP 22 is a potent CK2 inhibitor, with an IC 50 of 100 nM and a K I of 40 nM. TTP 22 shows no effect on other kianses such as Jnk3, Rock1, Tie2, Ask 1, met and FGFR1 at 10 μM. |